Materia is Latin for "material", and may refer to:
- Matter as described by conventional physics and chemistry
- Matter (philosophy) as contemplated by metaphysical philosophy
- Materials used in manufacturing
- Daihatsu Materia, a Japanese automobile
- Materia (Final Fantasy), part of the Final Fantasy VII video game mythos
- Materia (Novembre album), a 2006 album by the Italian metal band Novembre
- Materia (ukagaka), a well known ukagaka program
- Prima Materia is, according to alchemists, the alleged primitive formless base of all matter
- Prima Materia (album) is also the name of a Psybient album released by Bluetech
- Materia Magica, a well-known custom codebase MUD published by Ingenii Interactive that has been in operation since 1996
- Materia Medica Pura
- Materia medica, a Latin medical term for the body of collected knowledge about the therapeutic properties of any substance used for healing (i.e., medicines)
- Grand Materia, released in 2005, was the ninth studio album by Swedish heavy metal band Morgana Lefay
- Memento Materia, a Swedish record label focusing on synth-, electro- and futurepop, although it also released some EBM in the 1990s