Manhunter may refer to:

  • Manhunter (film), a 1986 film based on the novel Red Dragon
  • The Manhunter, a 1974 TV series set in the 1930s
  • Manhunters: Fugitive Task Force, a 2008 TV series
  • Manhunter (comics), numerous superheroes and villains from DC Comics
    • Manhunter (Kate Spencer)
    • Manhunters (comics), a fictional robot race in the DC Comics Universe
  • Manhunter: New York, a 1988 adventure game by Sierra Entertainment