Lorenzo may refer to:
People:
- Lorenzo (name), including a list of people with the given name or surname Lorenzo
Places:
- San Lorenzo, California, formerly Lorenzo
- Lorenzo, Texas
- Lorenzo State Historic Site, house in New York State listed on the National Register of Historic Places
Music:
- Lorenzo (song), a 1996 song by Phil Collins
In television and film:
- Lorenzo (film), Disney film about a cat
- Lorenzo's Oil, film about a boy suffering from ALD
- Lorenzo's Time, a 2012 Philippine TV Series aired in ABS-CBN