Kleist, or von Kleist, is a surname.
von Kleist:
- Ewald Jürgen Georg von Kleist (ca. 1700–1748), co-inventor of the Leyden jar
- Ewald Christian von Kleist (1715–1759), German poet and soldier
- Franz Kasimir von Kleist (1738–1808) Prussian General
- Franz Alexander von Kleist (1769–1799) Poet
- Friedrich Graf Kleist von Nollendorf (1762–1823), Prussian Field Marshal
- Heinrich von Kleist (1777–1811), German writer
- Kleist Prize, German literary prize named after Heinrich
- Paul Ludwig Ewald von Kleist (1881–1954), German Field Marshal
- Panzer Group Kleist and Army Group von Kleist, parts of the German First Panzer Army
- Ewald von Kleist-Schmenzin (1890–1945), conspirator to assassinate Adolf Hitler
- Ewald-Heinrich von Kleist-Schmenzin (born 1922), conspirator to assassinate Adolf Hitler
Kleist:
- Kleist Sykes, former Tanzanian mayor
- Henry Kleist, farmer and Socialist state senator from Rantoul, Wisconsin
- Kuupik Kleist, First Minister elect of Greenland
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