ITK (gene) - Structure

Structure

This protein contains the following domains, which are often found in intracellular kinases:

  • N-terminus – PH (pleckstrin homology domain)
  • BTK – Bruton's tyrosine kinase Cys-rich motif
  • SH3 – (Src homology 3)
  • SH2 – (Src homology 2)
  • C-terminus – tyrosine kinase, catalytic domain

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