Intention To Treat Analysis
An intention to treat (ITT) analysis of the results of an experiment is based on the initial treatment assignment and not on the treatment eventually received. ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random attrition of participants from the study or crossover. ITT is also simpler than other forms of study design and analysis because it does not require observation of compliance status for units assigned to different treatments or incorporation of compliance into the analysis. Although ITT analysis is widely employed in published clinical trials, it can be incorrectly described and there are some issues to its application.
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“Though it is possible to utter words only with the intention to fulfill the will of God, it is very difficult not to think about the impression which they will produce on men and not to form them accordingly. But deeds you can do quite unknown to men, only for God. And such deeds are the greatest joy that a man can experience.”
—Leo Tolstoy (18281910)
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