Intention To Treat Analysis - Issues

Issues

Medical investigators often have difficulties in accepting ITT analysis because of clinical trial issues like missing data or adherence to protocol.

To address some of these issues, many clinical trials have excluded participants after the random assignment in their analysis, which is often referred to as modified intention-to-treat analysis or mITT. Trials employing mITT have been linked to industry sponsorship and conflicts of interest by the authors.

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