Insulin-like Growth Factor 2 Receptor
Gene Ontology | |
---|---|
Molecular function | • glycoprotein binding • receptor activity • insulin-like growth factor-activated receptor activity • transporter activity • protein binding • insulin-like growth factor binding • mannose binding • phosphoprotein binding |
Cellular component | • nuclear envelope lumen • lysosomal membrane • endosome • integral to plasma membrane • cell surface • endocytic vesicle • trans-Golgi network transport vesicle |
Biological process | • receptor-mediated endocytosis • signal transduction • insulin-like growth factor receptor signaling pathway |
Sources: Amigo / QuickGO |
160.39 – 160.53 Mb
12.68 – 12.77 Mb
In the fields of biochemistry and cell biology, the insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is encoded by the IGF2R gene. IGF2R is a multifunctional protein receptor that binds insulin-like growth factor 2 (IGF2) at the cell surface and mannose-6-phosphate (M6P)-tagged proteins in the trans-Golgi network.
Read more about Insulin-like Growth Factor 2 Receptor: Structure, Function, Interactions
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