INI can be an acronym or a word that may mean:
Computing
- INI file, a configuration file for computer applications
- Impact Nominal Index, a computer system to track and trace individuals during criminal investigations
Organizations
- Isaac Newton Institute (INI)
- Instituto Nacional de Industria (INI), Spanish industrial development organization
- Inatsisartut Inissiaatileqatigiifik (INI), Greenland's public housing authority
- Instituto Nacional Indigenista (INI), Mexico's (defunct) government agency for indigenous people
- INI Steel, a group by Hyundai Motor Company
- Inspiration Network International, a Christian TV channel*
Places
- INI, the IATA code of Niš Constantine the Great Airport in Serbia
- Ini, Nigeria, an administrative division of Akwa Ibom State
Music
- INI (hip hop group), a hip hop music group
- Ini Kamoze, a Reggae artist
Other
- Ini, a king at Thebes, Egypt, during the 8th century BCE
- According to Rastafari philosophy, "I-N-I" a.k.a."I-and-I" is the personification of one who lives by Rastafari ideals, or specifically how one choses to view himself or herself.
- Ini (Stephen King), a term for an inter-dimensional portal in two books by author Stephen King, Desperation and The Regulators
- Institute of National Importance (INI), a status that may be conferred to a higher education institution in India by an act of parliament.