Imputation can refer to:
- Imputation (law), the concept that ignorance of the law does not excuse
- Imputation (statistics), substitution of some value for missing data
- Imputation (genetics), estimation of unmeasured genotypes
- Theory of imputation, the theory that factor prices are determined by output prices
- Imputation (game theory), a distribution that benefits each player who cooperates in a game
- Imputed righteousness, a concept in Christian theology
- Double imputation, a concept in Christian theology