Future Directions
Hyperthermia may be combined with gene therapy, particularly using the heat shock protein 70 promoter.
Two major technological challenges make hyperthermia therapy complicated: the ability to achieve a uniform temperature in a tumor, and the ability to precisely monitor the temperatures of both the tumor and the surrounding tissue. Advances in devices to deliver uniform levels of the precise amount of heat desired, and devices to measure the total dose of heat received, are hoped for.
In locally advanced adenocarcinoma of middle and lower rectum, regional hyperthermia added to chemoradiotherapy achieved good results in terms of rate of sphincter sparing surgery.
Read more about this topic: Hyperthermia Therapy
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—Neil Kurshan (20th century)
““Have we any control over being born?,” my friend asked in despair. “No, the job is done for us while we’re sleeping, so to speak, and when we wake up everything is all set. We merely appear, like an ornate celebrity wheeled out in a wheelchair.” “I don’t remember,” my friend claimed. “No need to,” I said: “what need have us free-loaders for any special alertness? We’re done for.””
—Marvin Cohen, U.S. author and humorist. The Self-Devoted Friend, New Directions (1967)