HST may refer to:
In science and technology:
- Hubble Space Telescope
- Harvard-MIT Division of Health Sciences and Technology
- Herschel Space Telescope, an alternate name for the Herschel Space Observatory
- History of Science and Technology
- High Speed Telegraphy, a radiosport
- USRobotics' HST (High-Speed Transfer) modem protocol
Places:
- Hospital Santo Tomas (Saint Thomas Hospital), a hospital in Panama City, Panama
Transportation:
- Helsinki City Transport, Swedish abbreviation
- Heritage Shunters Trust, a trade name of the South Yorkshire Railway Company
- High Street (Glasgow) railway station, Scotland with National Rail station code HST
- InterCity 125, a British train often called the High Speed Train
- High-Speed Tractor, a military vehicle including the M4, M5, M6 and M8, among others
Other uses:
- Harmonized Sales Tax, in Canada the combining of the federal Goods & Services Tax (GST) and Provincial Sales Tax (PST) into a single tax
- Hegemonic stability theory, a concept in international relations
- Helicopter support team, a team of eight landing support Marines
- Hypertrophy-specific Training, in weight lifting