HBF may refer to:

  • Half-band filter, signal processing filter
  • The Human Betterment Foundation, a eugenics organization established in 1928 by E.S. Gosney
  • Hemoglobin F or fetal hemoglobin, the form of hemoglobin found in the fetus
  • HBF Health Fund, a provider of private health insurance in Western Australia
  • Hauptbahnhof, German for central railway station