Gel Permeation Chromatography - Application

Application

GPC is often used to determine the relative molecular weight of polymer samples as well as the distribution of molecular weights. What GPC truly measures is the molecular volume and shape function as defined by the intrinsic viscosity. If comparable standards are used, this relative data can be used to determine molecular weights within ± 5% accuracy. Polystyrene standards with PDI of less than 1.2 are typically used to calibrate the GPC. Unfortunately, polystyrene tends to be a very linear polymer and therefore as a standard it is only useful to compare it to other polymers that are known to be linear and of relatively the same size.

Read more about this topic:  Gel Permeation Chromatography

Famous quotes containing the word application:

    The application requisite to the duties of the office I hold [governor of Virginia] is so excessive, and the execution of them after all so imperfect, that I have determined to retire from it at the close of the present campaign.
    Thomas Jefferson (1743–1826)

    There are very few things impossible in themselves; and we do not want means to conquer difficulties so much as application and resolution in the use of means.
    François, Duc De La Rochefoucauld (1613–1680)

    We will not be imposed upon by this vast application of forces. We believe that most things will have to be accomplished still by the application called Industry. We are rather pleased, after all, to consider the small private, but both constant and accumulated, force which stands behind every spade in the field. This it is that makes the valleys shine, and the deserts really bloom.
    Henry David Thoreau (1817–1862)