Types of Screens
ENU is used as a genetic tool by designing a variety of genetic screens suitable to the researchers' interests. Depending on the region being assessed, forward genetic screens can be classified as illustrated in Figure 2 as:
- Region Specific screens: Studies are designed specifically to obtain a gradient of phenotypes by generating an allelic series which are helpful in studying the region of interest.
- Genome-wide screens: These comprise of simple dominant or recessive screens and are often useful in understanding specific genetic and biochemical pathways.
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