Central Nervous System Constituent
DHA is the most abundant omega-3 fatty acid in the brain and retina. DHA comprises 40% of the polyunsaturated fatty acids (PUFAs) in the brain and 60% of the PUFAs in the retina. Fifty percent of the weight of a neuron's plasma membrane is composed of DHA. DHA is richly supplied during breastfeeding, and DHA levels are high in breastmilk regardless of dietary choices.
DHA modulates the carrier-mediated transport of choline, glycine, and taurine, the function of delayed rectifier potassium channels, and the response of rhodopsin contained in the synaptic vesicles, among many other functions.
DHA deficiency is associated with cognitive decline. Phosphatidylserine (PS) controls apoptosis, and low DHA levels lower neural cell PS and increase neural cell death. DHA are reduced in the brain tissue of severely depressed patients.
Read more about this topic: Docosahexaenoic Acid
Famous quotes containing the words central, nervous and/or system:
“The fantasies inspired by TB in the last century, by cancer now, are responses to a disease thought to be intractable and capricious—that is, a disease not understood—in an era in which medicine’s central premise is that all diseases can be cured.”
—Susan Sontag (b. 1933)
“Tea, though ridiculed by those who are naturally coarse in their nervous sensibilities ... will always be the favourite beverage of the intellectual.”
—Thomas De Quincey (1785–1859)
“Delight at having understood a very abstract and obscure system leads most people to believe in the truth of what it demonstrates.”
—G.C. (Georg Christoph)