CPAC may refer to:
- Conservative Political Action Conference, an annual gathering of conservative activists in the United States
- CPAC (TV channel), a Canadian legislature broadcaster television channel
- Carpenter Performing Arts Center, located on the campus of California State University, Long Beach
- Central Plains Athletic Conference, now known as the Manitoba Colleges Athletic Conference
- CPAC, Inc., the parent company of the Fuller Brush Company and Stanley Home Products
- The United States State Department's Cultural Property Advisory Committee