CLD can mean:
- Color Layout Descriptor (CLD) is designed to capture the spatial distribution of color in an image
- McClellan-Palomar Airport in Carlsbad, California (IATA Code: CLD)
- Causal Loop Diagram for modeling dynamic systems
- Current limiting diode in electronics
- CLD chromophore in organic chemistry and polymeric nonlinear optics
- Chronic liver disease
- Chronic lung disease
- Constrained-layer damping, a mechanical engineering technique for suppression of vibration
- Configurable Logic Device, synonym for PLD
- cld, the clear direction flag instruction on x86 compatible CPUs, opposite of std
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