CFE may refer to:
- Campaign for Fiscal Equity, a non-profit organization which advocates for funding of education in New York City
- Campaign for Free Education, a group in the National Union of Students (United Kingdom) opposed to tuition fees
- Capcom Fighting Evolution, a fighting game from Capcom
- Centre for Enterprise, a British company which manages and supports public programmes
- Certified Fraud Examiner, a designation awarded by the Association of Certified Fraud Examiners
- CFE (Belgium), a Belgian construction company of international standing
- CFE Company, producer of the CFE738 turbofan engine
- Chicago, Fort Wayne and Eastern Railroad, in the United States ((reporting mark)
- Clermont-Ferrand Auvergne Airport (IATA airport code)
- Comisión Federal de Electricidad, the Mexican state-owned electric power utility
- Common Firmware Environment, a bootloader developed by Broadcom for their system-on-a-chip products
- Continued fraction expansion, a continued fraction written as its integer members only
- Conventional Forces in Europe, from two NATO/Warsaw Pact treatises:
- Treaty on Conventional Armed Forces in Europe
- Adapted Conventional Armed Forces in Europe Treaty
- Confédération Fiscale Européenne, an organisation of European tax advisers and their national organisations
- Council of Five Elders, a government council of feudal Japan
- Curriculum for Excellence, the national curriculum for Scottish schools