Role of Intracranial Pressure
Increased intracranial pressure (ICP) causes decreased blood perfusion of brain cells by mainly two mechanisms:
- Increased ICP constitutes an increased interstitial hydrostatic pressure that, in turn, causes a decreased driving force for capillary filtration from intracerebral blood vessels.
- Increased ICP compresses cerebral arteries, causing increased cerebrovascular resistance (CVR).
Read more about this topic: Cerebral Blood Flow
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