Ex Vivo Blood Stimulation
Ex vivo blood stimulation is the process by which researchers can analyse the immunological biomarkers of drug effects in healthy volunteers. Blood samples (taken from healthy volunteers) are stimulated in the laboratory to activate the immune system. Ex vivo blood stimulation studies, therefore, allow the evaluation of the effect of a new compound in a "living system" in which the immune system has been challenged. Most research using this method is carried out by Phase I clinical research organisations, allowing them to collect blood samples and analyse them instantly so they do not deteriorate.
Read more about this topic: Biomarker Discovery
Famous quotes containing the words blood and/or stimulation:
“The Indian attitude toward the land was expressed by a Crow named Curly: “The soil you see is not ordinary soil—it is the dust of the blood, the flesh, and the bones of our ancestors. You will have to dig down to find Nature’s earth, for the upper portion is Crow, my blood and my dead. I do not want to give it up.””
—For the State of Montana, U.S. public relief program. Montana: A State Guide Book (The WPA Guide to Montana)
“The lore of our fathers is a fabric of sentences. In our hands it develops and changes, through more or less arbitrary and deliberate revisions and additions of our own, more or less directly occasioned by the continuing stimulation of our sense organs. It is a pale gray lore, black with fact and white with convention. But I have found no substantial reasons for concluding that there are any quite black threads in it, or any white ones.”
—Willard Van Orman Quine (b. 1908)