Entertainment
- Babe the Blue Ox, companion of the mythical lumberjack Paul Bunyan
- Babe, the title character of the Dick King-Smith book The Sheep-Pig
- Babe (film), a 1995 Australian film based on the book
- Babe: Pig in the City, the 1998 sequel
- The Babe (film), a 1992 film about famed baseball player Babe Ruth starring John Goodman
- Babe Carey, a character in the American soap opera All My Children
- Babe (comics), a comic book by artist/writer John Byrne
- Babe (band), a Serbian rock band
- BaBe, a Japanese Pop duo
- "Babe" (Styx song), a song on Styx's 1979 album Cornerstone
- "Babe" (Take That song), a number one hit single by the UK boy band Take That
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