Aparicio is both a surname and a given name. Notable people with the name include:
Surname:
- Carlos Enrique Aparicio (born 1985), Salvadoran football player
- Jose Aparicio (1773–1838), Spanish painter of the Neoclassic period
- Julio Aparicio Díaz (born 1969) Spanish bullfighter, known for getting gored through his mouth by a bull
- Luis Aparicio (born 1934), Venezuelan baseball player
- Nestor Aparicio (born 1968), American radio personality
- Rafaela Aparicio (1906–1996), Spanish film and theatre actress
- Sofia Aparício (born 1970), Portuguese model and actress
- Timoteo Aparicio, Uruguayan leader of the Revolution of the Lances
Given name:
- Aparicio Méndez (1904–1988), Uruguayan political leader
- Aparicio Saravia (1856–1904), Uruguayan political leader