Animal models of ischemic stroke are procedures inducing cerebral ischemia. The aim is the study of basic processes or potential therapeutic interventions in this disease, and the extension of the pathophysiological knowledge on and/or the improvement of medical treatment of human ischemic stroke. Ischemic stroke has a complex pathophysiology involving the interplay of many different cells and tissues such as neurons, glia, endothelium, and the immune system. These events cannot be mimicked satisfactorily in vitro yet. Thus a large portion of stroke research is conducted on animals.
Read more about Animal Models Of Ischemic Stroke: Overview, Mechanisms of Inducing Ischemic Stroke, Hypoxic Ischemia Models, Focal Ischemia Models
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—Samuel Butler (1835–1902)
“If thou and nature can so gently part,
The stroke of death is as a lover’s pinch,
Which hurts, and is desired.”
—William Shakespeare (1564–1616)