Animal Models of Ischemic Stroke - Focal Ischemia Models

Focal Ischemia Models

They are divided into techniques including reperfusion of the ischemic tissue (transient focal cerebral ischemia) and those without reperfusion (permanent focal cerebral ischemia). The following models are established :

  • Endothelin-1 -induced constriction of arteries and veins
  • Middle cerebral artery occlusion (MCAO)
    • MCAO avoiding craniotomy
      • Embolic middle cerebral artery occlusion
      • Endovascular filament middle cerebral artery occlusion (transient or permanent)
    • MCAO involving craniotomy
      • Permanent transcranial middle cerebral artery occlusion
      • Transient transcranial middle cerebral artery occlusion
  • Direct tissue damage
    • Cerebrocortical photothrombosis

Read more about this topic:  Animal Models Of Ischemic Stroke

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