Mechanisms of Inducing Ischemic Stroke
Some of the mechanisms which have been used are:
- Complete global ischemia
- Decapitation
- Aorta/vena cava occlusion
- External neck torniquet or cuff
- Cardiac arrest
- Incomplete global ischemia
- Hemorrhage or hypotension
- Hypoxic ischemia
- Intracranial hypertension and common carotid artery occlusion
- Two-vessel occlusion and hypotension
- Four-vessel occlusion
- Unilateral common carotid artery occlusion (in some species only)
- Focal cerebral ischemia
- Endothelin-1-induced constriction of arteries and veins
- Middle cerebral artery occlusion
- Spontaneous brain infarction (in spontaneously hypertensive rats)
- Macrosphere embolization
- Multifocal cerebral ischemia
- Blood clot embolization
- Microsphere embolization
- Photothrombosis
Read more about this topic: Animal Models Of Ischemic Stroke
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