Afolabi is a name of Yoruba origin that means "born in wealth and high status". Notable people with the name include:
- Afolabi Olabimtan (1932-2003), Nigerian politician and writer
- Ola Afolabi (born 1980), British boxer
- Olabisi Afolabi (born 1975), Nigerian athlete
- Rabiu Afolabi (born 1980), Nigerian footballer
- S. A. Afolabi (born 1966), Nigerian novelist and short story writer
- Oladapo Afolabi (born 1953), Nigerian academic and public servant
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