Affleck is a Scottish surname: it derives from Auchinleck and represents one of the pronunciations of that name. It may be pronounced with the stress on either syllable.
- People surnamed Affleck include
- B. F. Affleck (1869–1944), American cement businessman in the Chicago area
- Ben Affleck (born 1972), American actor, film director and screenwriter
- Bruce Affleck (born 1954), retired former professional ice hockey defenceman
- Casey Affleck (born 1975), American actor
- David Affleck (1912–1984), Scottish professional footballer
- Edmund Affleck (1725–1788), naval officer
- Francis Affleck (1950–1985), Canadian race car driver
- George Affleck (1888–?), Scottish footballer for Grimsby Town and Leeds City
- Gilbert Affleck (1684–1764), British politician
- John Affleck (1712–1776), British politician
- Neil Affleck, actor, animator and director
- Philip Affleck (1726–1799), British admiral, younger brother of Sir Edmund Affleck
- Simon Affleck (1660–1725), Swedish tax official
- Thomas Affleck (1745–1795), Pennsylvanian cabinetmaker
- Places called Affleck include
- Affleck, Aberdeenshire, Scotland
- Affleck Castle in Monikie, Angus, Scotland
- Other
- HMS Affleck (K462), World War II frigate named after Sir Edmund Affleck
- Afflecks, shopping complex in Manchester, Greater Manchester