Adverse Effect - Examples of Adverse Effects Associated With Specific Medications

Examples of Adverse Effects Associated With Specific Medications

  • Abortion, miscarriage or uterine hemorrhage associated with misoprostol (Cytotec), a labor-inducing drug (this is a case where the adverse effect has been used legally and illegally for performing abortions)
  • Addiction to many sedatives and analgesics, such as diazepam, morphine, etc.
  • Birth defects associated with thalidomide and isotretinoin (Accutane)
  • Bleeding of the intestine associated with aspirin therapy
  • Cardiovascular disease associated with COX-2 inhibitors (i.e. Vioxx)
  • Deafness and kidney failure associated with gentamicin (an antibiotic)
  • Death, following sedation, in children using propofol (Diprivan)
  • Dementia associated with coronary artery bypass surgery
  • Depression or hepatic injury caused by interferon
  • Diabetes caused by atypical antipsychotic medications (neuroleptic psychiatric drugs)
  • Diarrhea caused by the use of orlistat (Xenical)
  • Erectile dysfunction associated with many drugs, such as antidepressants
  • Fever associated with vaccination (in the past, imperfectly manufactured vaccines, such as Bacillus Calmette-GuĂ©rin (BCG) and poliomyelitis, have caused the very disease they intended to fight)
  • Glaucoma associated with corticosteroid-based eye drops
  • Hair loss and anemia may be caused by chemotherapy against cancer, leukemia, etc.
  • Headache following spinal anaesthesia
  • Hypertension in ephedrine users, which prompted FDA to remove the dietary supplement status of ephedra extracts
  • Insomnia caused by stimulants, methylphenidate (Ritalin), Adderall, etc.
  • Lactic acidosis associated with the use of stavudine (Zerit, for HIV therapy) or metformin (for diabetes)
  • Mania caused by corticosteroids
  • Liver damage from paracetamol
  • Melasma and thrombosis associated with use of estrogen-containing hormonal contraception, such as the combined oral contraceptive pill
  • Priapism associaded with the use of sildenafil
  • Rhabdomyolysis associated with statins (anticholesterol drugs)
  • Seizures caused by withdrawal from benzodiazepines
  • Drowsiness or increase in appetite due to antihistamine use. Some antihistamines are used in sleep aids explicitly because they cause drowsiness.
  • Stroke or heart attack associated with sildenafil (Viagra), when used with nitroglycerin
  • Suicide, increased tendency associated to the use of fluoxetine and other selective serotonin reuptake inhibitor (SSRI) antidepressants
  • Tardive dyskinesia associated with long-term use of metoclopramide and many antipsychotic medications

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