5-HT1B Receptor

5-HT1B Receptor

Identifiers Symbols HTR1B; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12 External IDs OMIM: 182131 MGI: 96274 HomoloGene: 669 IUPHAR: 5-HT_1B ChEMBL: 1898 GeneCards: HTR1B Gene

Gene Ontology
Molecular function	• serotonin receptor activity • drug binding • serotonin binding
Cellular component	• cytoplasm • plasma membrane • integral to plasma membrane
Biological process	• G-protein coupled receptor internalization • G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • protein kinase C-activating G-protein coupled receptor signaling pathway • synaptic transmission • regulation of dopamine secretion • negative regulation of cAMP biosynthetic process • negative regulation of synaptic transmission, GABAergic • response to cocaine • response to drug • drinking behavior • response to ethanol • bone remodeling • response to mineralocorticoid stimulus • negative regulation of synaptic transmission, glutamatergic • cellular response to temperature stimulus
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 3351 15551 Ensembl ENSG00000135312 ENSMUSG00000049511 UniProt P28222 P28334 RefSeq (mRNA) NM_000863 NM_010482 RefSeq (protein) NP_000854 NP_034612 Location (UCSC) Chr 6:
78.17 – 78.17 Mb Chr 9:
81.63 – 81.63 Mb PubMed search

5-hydroxytryptamine receptor 1B also known as the 5-HT_1B receptor is a protein that in humans is encoded by the HTR1B gene. The 5-HT_1B receptor is a 5-HT receptor subtype.