Schedule
See also: 2008 NCAA Division I FBS football rankings| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| September 1 | 8:00 PM | at UCLA* | #18 | Rose Bowl • Pasadena, CA | ESPN | L 24–27 OT | 68,546 | |
| September 13 | 12:30 PM | UAB* | Neyland Stadium • Knoxville, TN | Raycom | W 35–3 | 98,205 | ||
| September 20 | 3:30 PM | #4 Florida | Neyland Stadium • Knoxville, TN (Third Saturday in September) | CBS | L 6–30 | 106,138 | ||
| September 27 | 3:30 PM | at #16 Auburn | Jordan–Hare Stadium • Auburn, AL | CBS | L 12–14 | 87,451 | ||
| October 4 | 7:00 PM | Northern Illinois* | Neyland Stadium • Knoxville, TN | PPV | W 13–9 | 99,539 | ||
| October 11 | 3:30 PM | at #10 Georgia | Sanford Stadium • Athens, GA | CBS | L 14–26 | 92,746 | ||
| October 18 | 7:00 PM | Mississippi State | Neyland Stadium • Knoxville, TN | PPV | W 34–3 | 98,239 | ||
| October 25 | 7:45 PM | #2 Alabama | Neyland Stadium • Knoxville, TN (Third Saturday in October) | ESPN | L 9–29 | 106,138 | ||
| November 1 | 7:00 PM | at South Carolina | Williams-Brice Stadium • Columbia, SC (The Halloween Game) | ESPN2 | L 6–27 | 81,731 | ||
| November 8 | 1:00 PM | Wyoming* | Neyland Stadium • Knoxville, TN | L 7–13 | 99,489 | |||
| November 22 | 12:30 PM | at Vanderbilt | Vanderbilt Stadium • Nashville, TN | Raycom | W 20–10 | 38,725 | ||
| November 29 | 6:30 PM | Kentucky | Neyland Stadium • Knoxville, TN (Battle for the Barrel) | ESPN2 | W 28–10 | 102,388 | ||
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