Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| August 30 | 7:00 PM | James Madison* | Wallace Wade Stadium • Durham, NC | ACCS | W 31–7 | 32,571 | ||
| September 6 | 7:00 PM | Northwestern* | Wallace Wade Stadium • Durham, NC | ACCS | L 20–24 | 23,614 | ||
| September 13 | 12:00 PM | Navy* | Wallace Wade Stadium • Durham, NC | ESPNU | W 41–31 | 25,082 | ||
| September 27 | 12:00 PM | Virginia | Wallace Wade Stadium • Durham, NC | ESPNU | W 31–3 | 25,527 | ||
| October 4 | 12:00 PM | at Georgia Tech | Bobby Dodd Stadium • Atlanta, GA | ESPNU | L 0–27 | 46,104 | ||
| October 18 | 3:30 PM | Miami | Wallace Wade Stadium • Durham, NC | ESPNU | L 31–49 | 32,011 | ||
| October 25 | 3:00 PM | at Vanderbilt* | Vanderbilt Stadium • Nashville, TN | W 10–7 | 38,270 | |||
| November 1 | 3:30 PM | at Wake Forest | BB&T Field • Winston-Salem, NC (Tobacco Road Rivalry) | ESPN360 | L 33–30 OT | 32,336 | ||
| November 8 | 3:30 PM | NC State | Wallace Wade Stadium • Durham, NC (Research Triangle rivalry) | ESPN360 | L 27–17 | 31,964 | ||
| November 15 | 12:00 PM | at Clemson | Memorial Stadium • Clemson, SC | Raycom | L 31–7 | 76,217 | ||
| November 22 | 5:30 PM | at Virginia Tech | Lane Stadium • Blacksburg, VA | ESPNU | L 14–3 | 66,233 | ||
| November 29 | 3:30 PM | North Carolina | Wallace Wade Stadium • Durham, NC (Battle for the Victory Bell) | ESPNU | L 28–20 | 30,322 | ||
Read more about this topic: 2008 Duke Blue Devils Football Team