USCA may refer to:
- University of South Carolina Aiken
- Ulster Special Constabulary Association
- United States Code Annotated
- United States Court of Appeals
- University of Canterbury Students' Association
- University Students' Cooperative Association, a student housing cooperative in Berkeley, California, United States
- Federal Republic of Central America, also known as the United Provinces of Central America and (inaccurately) the United States of Central America
- United States Croquet Association
- United States Curling Association
- United States of Central America
- USCA Foot, a Malagasy football club
- United States Conference on AIDS
- United States Canoe Association
- US Collegiate Archery