The term Lees can refer to:
- Lees (fermentation) dead yeast and debris left after fermentation of wine, beer, etc.;
- Lees, Derbyshire, a village in England;
- Lees, Greater Manchester, village near Oldham in North West England;
- JW Lees, a Brewery in Middleton, Greater Manchester, England;
- Lees Station, Tennessee, a community in the U.S. state of Tennessee;
- Laboratory for Electromagnetic and Electronic Systems, Massachusetts Institute of Technology (MIT)
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