Kyo can refer to:
- Anime and manga
- Demon Eyes Kyo, a character in the manga series Samurai Deeper Kyo
- Kyo, a manga comic created by Ryōji Minagawa in 1996
- Kyo Sohma, a character in the manga and anime series Fruits Basket
- Music
- An alias of English singer-songwriter Carol Leeming
- Kyo (band), a French rock band
- Kyo (musician), Japanese musician, poet and singer-songwriter; vocalist for the Japanese metal band Dir En Grey
- Places
- Three villages in County Durham, England:
- East Kyo
- West Kyo
- New Kyo
- another name for Kyoto, a city in Japan
- Other
- Kyo Kusanagi, one of the main characters of the King of Fighters series of video games
- Kyō Fujibayashi, a character in the visual novel Clannad