Problems and Limitations
All implicit solvation models rest on the simple idea that nonpolar atoms of a solute tend to cluster together or occupy nonpolar media, whereas polar and charged groups of the solute tend to remain in water. However, it is important to properly balance the opposite energy contributions from different types of atoms. Several important points have been discussed and investigated over the years.
Read more about this topic: Implicit Solvation
Famous quotes containing the words problems and/or limitations:
“Currently, U.S. society has been encouraged by its political and subsidized mass-media intelligentsia to view U.S. life as a continual “morning in America” paradise, where the only social problems occur in the inner cities. Psychologists call this denial.”
—Ishmael Reed (b. 1938)
“To note an artist’s limitations is but to define his talent. A reporter can write equally well about everything that is presented to his view, but a creative writer can do his best only with what lies within the range and character of his deepest sympathies.”
—Willa Cather (1876–1947)