HFL may refer to:
- Highland Football League, a football league in Scotland
- Hollandse Florijn (Dutch Florin), used in the Netherlands from 1279-2002
- Honeoye Falls-Lima Central School District, a public school district located in Honeoye Falls, New York
- Hokushin'etsu Football League, one of nine Japanese Regional Leagues of association football in Japan
- Hydrofluoric acid in chemistry