Hereditary Nonpolyposis Colorectal Cancer

Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.

Read more about Hereditary Nonpolyposis Colorectal Cancer:  Terminology, Classification, Genetics, Screening, Diagnosis, Treatment, Epidemiology

Famous quotes containing the words hereditary and/or cancer:

    We bring [to government] no hereditary status or gift of infallibility and none follows us from this place.
    Gerald R. Ford (b. 1913)

    I’m beginning to believe that Killer Illiteracy ought to rank near heart disease and cancer as one of the leading causes of death among Americans. What you don’t know can indeed hurt you, and so those who can neither read nor write lead miserable lives, like Richard Wright’s character, Bigger Thomas, born dead with no past or future.
    Ishmael Reed (b. 1938)