Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.
Read more about Hereditary Nonpolyposis Colorectal Cancer: Terminology, Classification, Genetics, Screening, Diagnosis, Treatment, Epidemiology
Famous quotes containing the words hereditary and/or cancer:
“We bring [to government] no hereditary status or gift of infallibility and none follows us from this place.”
—Gerald R. Ford (b. 1913)
“Ever since I was a kid my folks fed me bigotry for breakfast and ignorance for supper. Never, not once did they ever make me feel proud of where I was born. That’s it. That was a cancer they put in me. No knowledge of my country. No pride. Just a hymn of hate.”
—Samuel Fuller (b. 1911)