Colon may refer to:
- Colon (anatomy), the final section of the digestive system
- Colon (punctuation), the punctuation mark :
- Colon (rhetoric), a clause which is grammatically, but not logically, complete
- Colon classification, a library classification system named for the use of the punctuation mark
- Colon, Michigan, village located within Colon Township
- Colon, Nebraska, village in Saunders County