Some articles on lynch syndrome:
PMS2 - Mutations
... germline mutations in DNA mismatch repair genes like PMS2 lead to autosomal dominant Lynch syndrome ... Only 2% of families that have Lynch syndrome have mutations in the PMS2 gene ... when they first presented with PMS2-associated Lynch syndrome varies greatly, with a reported range of 23 to 77 years ...
... germline mutations in DNA mismatch repair genes like PMS2 lead to autosomal dominant Lynch syndrome ... Only 2% of families that have Lynch syndrome have mutations in the PMS2 gene ... when they first presented with PMS2-associated Lynch syndrome varies greatly, with a reported range of 23 to 77 years ...
Amsterdam Criteria - Alternatives
... for the identification of individuals who should receive genetic testing for Lynch syndrome related tumors ... metachronous (at another time i.e.- a re-occurrence of) CRC or other Lynch syndrome-associated tumors, regardless of age CRC with high microsatellite instability histology diagnosed in a ... II Criteria in detecting individuals and families at risk of Lynch syndrome ...
... for the identification of individuals who should receive genetic testing for Lynch syndrome related tumors ... metachronous (at another time i.e.- a re-occurrence of) CRC or other Lynch syndrome-associated tumors, regardless of age CRC with high microsatellite instability histology diagnosed in a ... II Criteria in detecting individuals and families at risk of Lynch syndrome ...
Famous quotes containing the words syndrome and/or lynch:
“Women are taught that their main goal in life is to serve others—first men, and later, children. This prescription leads to enormous problems, for it is supposed to be carried out as if women did not have needs of their own, as if one could serve others without simultaneously attending to one’s own interests and desires. Carried to its “perfection,” it produces the martyr syndrome or the smothering wife and mother.”
—Jean Baker Miller (20th century)
“Johnson’s conversation was by much too strong for a person accustomed to obsequiousness and flattery; it was mustard in a young child’s mouth.”
—Hester Lynch Thrale (1739–1821)