FSC may refer to:
- Education
- Fitchburg State College, a college in Fitchburg, Massachusetts
- Florida Southern College, a college in Lakeland, Florida
- Florida Sun Conference, an athletic conference of the National Association of Intercollegiate Athletics
- Framingham State College, a college in Framingham, Massachusetts
- Fratres Scholarum Christianorum, the Institute of the Brothers of the Christian Schools; a Roman Catholic religious teaching order
- Companies
- Fabryka Samochodów Ciężarowych, a large automobile factory in Poland
- Fujitsu Siemens Computers
- Governmental agencies
- Texas Forensic Science Commission
- Other organisations
- The FidoNet Standards Committee
- Field Studies Council, a British environmental education charity
- Financial Services Commission (formerly Financial Supervisory Commission), South Korea's financial regulator
- Financial Services Commission, Gibraltar's financial regulator
- Financial Supervisory Commission, financial industry regulator in the Republic of China
- Forest School Camps, a British camping organisation
- Forest Stewardship Council, not-for-profit international organization setting standards and certification for environmentally responsible use of commercialized forests.
- The Free Speech Coalition, a trade association for the adult film and pornography industry
- The First Satanic Church, an organization dedicated to Satanism and the occult
- Other
- Fine-structure constant
- Fourier shell correlation
- Foo Swee Chin, a Singaporean comic book artist
- Foreign Sales Corporation
- Forward Schedule of Change (ITIL terminology)
- Fox Soccer Channel, a former name of Fox Soccer, a television network covering soccer (association football)
- the Future Surface Combatant program, intended to replace Type 22 and Type 23 frigates of the Royal Navy
- Fire-Safe cigarette
- The IATA airport code for Figari Sud-Corse Airport on the island of Corsica