Cwm may refer to:
- the geographical term for a rounded, glaciated valley also known as a corrie or cirque
- the Welsh word for a valley, sometimes anglicized to coombe
- In places
- Cwm, Blaenau Gwent, a community in Wales
- Cwm, Denbighshire, a community in Wales
- Western Cwm, a geographical feature on Mount Everest
- Cwm, Llanrothal, a Jesuit gathering place, and farmhouse in Herefordshire, England
- In other uses
- cwm (software), a general-purpose data processor for the semantic web
- cwm (window manager) for X Window System
- Cwm Rhondda, a famous Welsh hymn tune
- As an abbreviation
- Canadian War Museum
- Christian Witness Ministries
- Circus World Museum
- Clark-Wilson model
- Comes With Music, Nokia's digital music service
- Common Warehouse Metamodel, a data warehousing specification
- Council for World Mission
- Cwmbran railway station