Zileuton - Chemistry

Chemistry

Zileuton is an active oral inhibitor of the enzyme 5-lipoxygenase, which forms leukotrienes from arachidonic acid. The chemical name of zileuton is (±)-1-(1-Benzothien-2-ylethyl)-l-hydroxyurea.

The molecular formula of zileuton is C11H12N2O2S with a molecular weight of 236.29. The formulation from the manufacturer is a racemic mixture of R(+) and S(-) enantiomers.

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