Yap1

YAP1

Identifiers Symbols YAP1; YAP; YAP2; YAP65; YKI External IDs OMIM: 606608 MGI: 103262 HomoloGene: 4452 GeneCards: YAP1 Gene

Gene Ontology
Molecular function	• RNA polymerase II transcription factor binding transcription factor activity • chromatin binding • transcription coactivator activity • transcription corepressor activity • protein binding • transcription regulatory region DNA binding • proline-rich region binding
Cellular component	• nucleus • nucleoplasm • transcription factor complex • cytoplasm • cytosol
Biological process	• vasculogenesis • embryonic heart tube morphogenesis • transcription initiation from RNA polymerase II promoter • response to DNA damage stimulus • cell proliferation • positive regulation of cell proliferation • gene expression • regulation of keratinocyte proliferation • keratinocyte differentiation • negative regulation of epithelial cell differentiation • notochord development • somatic stem cell maintenance • hippo signaling cascade • negative regulation of apoptotic process • positive regulation of transcription from RNA polymerase II promoter • positive regulation of organ growth • paraxial mesoderm development • lateral mesoderm development • contact inhibition • cellular response to gamma radiation • regulation of stem cell proliferation • positive regulation of canonical Wnt receptor signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 10413 22601 Ensembl ENSG00000137693 ENSMUSG00000053110 UniProt P46937 P46938 RefSeq (mRNA) NM_001130145 NM_001171147 RefSeq (protein) NP_001123617 NP_001164618 Location (UCSC) Chr 11:
101.98 – 102.1 Mb Chr 9:
7.93 – 8 Mb PubMed search

65 kDa Yes-associated protein is a protein that in humans is encoded by the YAP1 gene.