Xpo1

XPO1

Identifiers Symbols XPO1; CRM1; emb; exp1 External IDs OMIM: 602559 MGI: 2144013 HomoloGene: 2554 ChEMBL: 5661 GeneCards: XPO1 Gene

Gene Ontology
Molecular function	• RNA binding • transporter activity • protein binding • protein transporter activity • protein domain specific binding
Cellular component	• kinetochore • nuclear envelope • annulate lamellae • nuclear pore • nucleoplasm • nucleolus • cytoplasm • cytosol • Cajal body • ribonucleoprotein complex
Biological process	• M phase of mitotic cell cycle • negative regulation of transcription from RNA polymerase II promoter • mitotic prometaphase • mitotic cell cycle • protein export from nucleus • transforming growth factor beta receptor signaling pathway • gene expression • regulation of centrosome duplication • viral reproduction • RNA metabolic process • mRNA metabolic process • virus-host interaction • viral infectious cycle • negative regulation of transforming growth factor beta receptor signaling pathway • protein localization to nucleus • regulation of protein catabolic process • response to drug • regulation of protein export from nucleus • mRNA transport
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7514 103573 Ensembl ENSG00000082898 ENSMUSG00000020290 UniProt O14980 Q6P5F9 RefSeq (mRNA) NM_003400 NM_001035226 RefSeq (protein) NP_003391 NP_001030303 Location (UCSC) Chr 2:
61.7 – 61.77 Mb Chr 11:
23.26 – 23.3 Mb PubMed search

Exportin-1 is a protein that in humans is encoded by the XPO1 gene.