Xeno may refer to:

  • Xeno Müller (born 1972), Swiss athlete
  • Xeno, Salamis, an area in Salamis Island
In media
  • Xeno Assault II, a video game
  • The Xeno series of role-playing video games
    • Xenogears, a role-playing video game released by Square in 1998
    • Xenosaga, a role-playing video game series developed by Monolith Soft and released by Namco from 2002 to 2006
    • Xenoblade Chronicles, a role-playing video game developed by Monolith Soft and released by Nintendo in 2010
  • Xenophilius Lovegood, a fictional character in J.K. Rowling's Harry Potter series
  • Xenomorphs, are a fictional endoparasitoid extraterrestrial species from the Alien film series
  • "Xenochrist", a song on the album Planetary Duality by The Faceless
  • Xenosapien, an album by grindcore band Cephalic Carnage
In games
  • Xeno (sphere ball game), a checkers-like game played on a velcro'd ball