Wertheimer is an Ashkenazi Jewish surname:
People with this surname include:
- Alain & Gerard Wertheimer, French Jewish billionaires owners of Chanel
- Egon Ranshofen-Wertheimer (1894-1957), Austrian and German diplomat, journalist, jurist and political scientist
- Esther Wertheimer, Polish architect
- François Wertheimer, French singer fr:François Wertheimer
- Fred Wertheimer, American political activist
- Haim Ernst Wertheimer, German-born Israeli biochemist
- Jack Wertheimer, professor of American Jewish history
- Jacques Wertheimer, father of Pierre
- Arjeh Yehuda Wertheimer (1862-1937), known as Constantin Brunner, German-Jewish philosopher
- Linda Wertheimer, American broadcast journalist for National Public Radio
- Max Wertheimer (1880- 1943), Prague-born Gestalt psychologist
- Michael Wertheimer, American cryptologic mathematician
- Pierre Wertheimer, co-founder of Chanel
- Rabbi Samson Wertheimer (1658-1724), German-Hungarian and Austrian rabbi, philanthropist
- Rabbi Solomon Aaron Wertheimer
- Stef Wertheimer (born 1926), Israeli industrialist
- Yair Wertheimer, Israeli tennis player