Werner Syndrome - Onset

Onset

Although the symptoms manifest after 10 years, the earliest person diagnosed was six years old. Following puberty, they age rapidly, so that by age 40, they often appear several decades older.

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Famous quotes containing the word onset:

    While the onset of puberty can vary by as much as six years, every adolescent wants to be right on the 50-yard line, right in the middle of the field. One is always too tall, too short, too thin, too fat, too hairy, too clear-skinned, too early, too late. Understandably, problems of self-image are rampant.
    Joan Lipsitz (20th century)