Unintentional Weight Loss
Unintentional weight loss occurs in many diseases and conditions, including some very serious diseases such as cancer, AIDS, and a variety of other diseases.
Poor management of type 1 diabetes mellitus, also known as insulin-dependent diabetes mellitus (IDDM), leads to an excessive amount of glucose and an insufficient amount of insulin in the bloodstream. This triggers the release of triglycerides from adipose (fat) tissue and catabolism (breakdown) of amino acids in muscle tissue. This results in a loss of both fat and lean mass, leading to a significant reduction in total body weight. Untreated type 1 diabetes mellitus can produce weight loss. In addition to weight loss due to a reduction in fat and lean mass, fluid loss can be triggered by illnesses such as diabetes, certain medications, lack of fluid intake or other factors. Fluid loss in addition to reduction in fat and lean mass exacerbates the risk for cachexia.
Infections such as HIV may alter metabolism, leading to weight loss.
Hormonal disruptions, such as an overactive thyroid (hyperthyroidism), may also exhibit as weight loss.
One cutoff value of where unintentional weight loss is of significant concern is where there's a weight loss of more than 5% in the past month, or at least 10% during the last 6 months.
Read more about this topic: Weight Loss
Famous quotes containing the words weight and/or loss:
“But I saw the little-Ant men as they ran
Carrying the worlds weight of the worlds filth
And the filth in the heart of Man
Compressed till those lusts and greeds had a greater heat
than that of the Sun.”
—Dame Edith Sitwell (18871964)
“Yet whatever gains I had, these I have come to regard as loss because of Christ. More than that, I regard everything as loss because of the surpassing value of knowing Christ Jesus my Lord. For his sake I have suffered the loss of all things, and I regard them as rubbish, in order that I may gain Christ and be found in him, not having a righteousness of my own that comes from the law, but one that comes through faith in Christ, the righteousness from God based on faith.”
—Bible: New Testament, Philippians 3:7-9.