Inheritance
This condition is usually inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to cause the disorder. In most cases, an affected person has one parent with the condition. A small percentage of cases result from new mutations in the gene; these cases occur in people with no history of the disorder in their family.
Some cases of type II and type IV Waardenburg syndrome appear to have an autosomal recessive pattern of inheritance, which means two copies of the gene must be altered for a person to be affected by the disorder. Most often, the parents of a child with an autosomal recessive disorder are not affected but are carriers of one copy of the altered gene.
-
Waardenburg syndrome is usually inherited in an autosomal dominant pattern.
-
Types II and IV Waardenburg syndrome may sometimes have an autosomal recessive pattern of inheritance.
Read more about this topic: Waardenburg Syndrome
Famous quotes containing the word inheritance:
“Late in the afternoon we passed a man on the shore fishing with a long birch pole.... The characteristics and pursuits of various ages and races of men are always existing in epitome in every neighborhood. The pleasures of my earliest youth have become the inheritance of other men. This man is still a fisher, and belongs to an era in which I myself have lived.”
—Henry David Thoreau (1817–1862)
“Every third year you shall bring out the full tithe of your produce for that year, and store it within your towns; the Levites, because they have no allotment or inheritance with you, as well as the resident aliens, the orphans, and the widows in your towns, may come and eat their fill so that the LORD your God may bless you in all the work that you undertake.”
—Bible: Hebrew, Deuteronomy 14:28,29.
“A child is born with the potential ability to learn Chinese or Swahili, play a kazoo, climb a tree, make a strudel or a birdhouse, take pleasure in finding the coordinates of a star. Genetic inheritance determines a child’s abilities and weaknesses. But those who raise a child call forth from that matrix the traits and talents they consider important.”
—Emilie Buchwald (20th century)